We'd like to understand how you use our websites in order to improve them. Register your interest. We revised clinical files of patients with brain astrocytomas treated at the Mexican National Institutes of Cancer, and Neurology and Neurosurgery. Prognostic factors, survival and disease free survival were analyzed.
|Published (Last):||21 December 2004|
|PDF File Size:||5.5 Mb|
|ePub File Size:||17.72 Mb|
|Price:||Free* [*Free Regsitration Required]|
Introduction: Since the introduction of genetic and molecular criteria in the World Health Organization WHO classification of brain tumours, there has been a diagnostic reclassification between certain astrocytomas and oligodendro-gliomas with histological and genetic discordances, the prognosis of which is unknown. Aim: To analyse the implications of the diagnostic reclassification of brain gliomas according to the WHO criteria, especially depending on isocitrate dehydrogenase IDH mutation and 1p19q codeletion.
Patients and methods: We conducted a retrospective study of gliomas treated from 1 January to 31 December , with analyses of clinicoradiological aspects and prognoses, and with available and complete follow-up until 31 March Results: From a total of brain gliomas, a molecular diagnosis and a diagnostic re-evaluation were carried out in 69 cases grade II-IV astrocytomas or oligodendrogliomas.
Twenty-four reclassified gliomas were detected, usually oligodendro-gliomas that became astrocytomas, and which showed greater survival, derived from their not being classified as grade IV. The prognostic factors were: young age, focus, grade II and no contrast enhancement or necrosis, or multiplicity.
Clipboard, Search History, and several other advanced features are temporarily unavailable. Search: Search. Advanced Clipboard. Create file Cancel. Email citation To:. Format: Summary Summary text Abstract Abstract text. Send email Cancel. Add to Collections Create a new collection Add to an existing collection.
Name your collection: Name must be less than characters. Choose a collection: Unable to load your collection due to an error Please try again. Add Cancel. Add to My Bibliography My Bibliography. Unable to load your delegates due to an error Please try again. Your saved search Name of saved search:. Search terms:. Test search terms. Would you like email updates of new search results?
Email: change. Frequency: Monthly Weekly Daily. Which day? Send at most: 1 item 5 items 10 items 20 items 50 items items items. Send even when there aren't any new results. Optional text in email:. Save Cancel. Create a file for external citation management software Create file Cancel. Full-text links Cite Favorites. Abstract in English , Spanish.
Similar articles Assessment of the impact of glioma diagnostic reclassification following the new WHO classification on a series of cases. Neurocirugia Astur. Epub Oct Leu K, et al. J Neurooncol. Epub May PMID: Molecular genetics of adult grade II gliomas: towards a comprehensive tumor classification system. Figarella-Branger D, et al. Epub Aug Histomolecular classification of adult diffuse gliomas: the diagnostic value of immunohistochemical markers. Rev Neurol Paris. Epub Sep 1. PMID: Review.
Tailored therapy in diffuse gliomas: using molecular classifiers to optimize clinical management. Taylor JW, et al. Oncology Williston Park. Show more similar articles See all similar articles. Publication types English Abstract Actions. Full-text links [x] Viguera Editores, S. Copy Download.
Astrocitomas cerebrales. Factores pronósticos en una serie de pacientes tratados en México