Enter your email and we'll keep you on top of the latest nutrition research, supplement myths, and more. Our evidence-based analysis on pelargonium sidoides features 79 unique references to scientific papers. Each member of our research team is required to have no conflicts of interest, including with supplement manufacturers, food companies, and industry funders. The team includes nutrition researchers, registered dietitians, physicians, and pharmacists.
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Enter your email and we'll keep you on top of the latest nutrition research, supplement myths, and more. Our evidence-based analysis on pelargonium sidoides features 79 unique references to scientific papers. Each member of our research team is required to have no conflicts of interest, including with supplement manufacturers, food companies, and industry funders.
The team includes nutrition researchers, registered dietitians, physicians, and pharmacists. We have a strict editorial process. This page features 79 references. All factual claims are followed by specifically-applicable references. Click here to see the full set of references for this page. Pelargonium sidoides , commonly known as African geranium, is a medicinal herb. It is also sold under the brand names Kaloban and Umckaloabo as a plant-derived pharmaceutical. Pelargonium sidoides is very effective for treating acute bronchitis.
Some people reported experiencing benefits after just two to three days. People that are not cured after a week still experience benefits from Pelargonium sidoides supplementation, since it can treat the symptoms associated with bronchitis, including headache, fever, fatigue, cough, chest pain while coughing, sputum in the lungs, rhonchi, and nasal dripping.
Preliminary evidence suggests Pelargonium sidoides can reduce the duration of the common cold, while treating symptoms. It may also provide benefits for people suffering from lung disorders, by alleviating flare-ups in symptoms. Pelargonium sidoides has anti-infective properties.
It prevents bacteria from adhering to cells, helps fight viruses and stimulates the immune system to hunt down invaders. Pelargonium sidoides may be able to fight Helicobacter pylori infection, which is the stomach bacteria that causes stomach ulcers. Pelargonium sidoides may also reduce the replication of the herpes simplex virus. The extract is concentrated to , so there is some variability with the recommended dosages.
To supplement the extract, take 4. Dosages vary by age:. While the vast majority of studies have used EPs specifically, any hydroalcoholic water and ethanol extraction equal to mg of the plant can be used as an alternative. By becoming an Examine Plus member , you'll have access to all of the latest nutrition research.
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We neatly summarize all the latest research so you can make the best decisions for your health based on what's accurate and not out-dated information. Pelargonidin Isolated anthocyanin , Ginkgo biloba EGb This plant appears to be somewhat threatened at this point in time due to unsustainable harvesting techniques.
Tired of misinformation? Get unbiased info on supplements. At Examine. We take an independent, unbiased approach to figure out what works and what's a waste of time and money. Arm yourself with the knowledge you need to make the right decisions about your health. Click here to see the full set of research information and references for Pelargonium sidoides. If using any pharmaceuticals or drugs given to you by a doctor or received with a prescription, you must consult with the doctor in question or an equally qualified Health Care Professional prior to using any nutritional supplementation.
If undergoing medical therapies, then consult with your respective Therapist or Health Care Professional about possible interactions between your Treatment, any Pharmaceuticals or Drugs being given, and possible nutritional supplements or practices hosted on Examine.
Join Examine. Don't miss out on the latest nutrition and supplement research Enter your email and we'll keep you on top of the latest nutrition research, supplement myths, and more. I'm ready to learn. It may also act as an immune system booster, and alleviate symptoms of the common cold and herpes.
This page is regularly updated, to include the most recently available clinical trial evidence. Research analysis led by Kamal Patel. Reviewed by Examine. NEW: Our free Coronavirus guide to staying healthy and sane while stuck indoors. Summary of Pelargonium sidoides Primary information, health benefits, side effects, usage, and other important details. You must be logged before you can follow this page. Login Register.
You are now following Pelargonium sidoides. You will be notified when any significant update is made. Want to know which supplements you should take? Includes free lifetime updates so you always have the most accurate information. How to Take Medical Disclaimer Recommended dosage, active amounts, other details. Human Effect Matrix. The Human Effect Matrix looks at human studies it excludes animal and in vitro studies to tell you what effects pelargonium sidoides has on your body, and how strong these effects are.
Grade Level of Evidence [show legend] Robust research conducted with repeated double-blind clinical trials Multiple studies where at least two are double-blind and placebo controlled Single double-blind study or multiple cohort studies Uncontrolled or observational studies only. Level of Evidence? The amount of high quality evidence. The more evidence, the more we can trust the results.
The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect. Scientific research does not always agree. Symptoms of Acute Bronchitis. There isn't an improvement in other lung disorders though, so this is more reflective of treatment of acute bronchitis. Lung Function. Secondary to treating sickness bronchitis, URTIs, common cold there is improvement in sputum content, rhonchi, breathing, coughing, and chest pain while coughing relative to placebo; while the improvements are marked, they only occur secondary to treating illness.
Treatment of Headaches. Headaches as a side effect of acute bronchitis are pretty much abolished with the treatment of acute bronchitis from this herb; it is doubtful that headaches from other causes aside from sickness are treated in a similar manner. Nasal Congestion. Nasal congestion appears to be decreased with supplementation of this herb, and while this is noted in acute bronchitis most potently it also affects other bacterial or viral instances such as the common cold and acute rhinosinitus.
Fatigue as a side-effect of acute bronchitis is reduced quite respectably relative to placebo. Subjective Well-Being. Alongside improvements in sickness comes improved well being and vitality associated with supplementation over placebo. Immunoglobulin A. Symptoms of the Common Cold. All symptoms appear to be reduced with treatment of the standard dose of EPs With symptom reduction after five days and the amount of persons with full resolution of symptoms being more than doubled relative to placebo.
There appears to be an increase in appetite during sickness in those given this supplement, and surprisingly this may not be limited to acute bronchitis.
In children with upper respiratory tract infections and asthma, the amount of asthmatic attacks during sickness appears to be slightly but significantly reduced relative to placebo. Exercise-Induced Immune Suppression. Severity of Sickness. In children with upper respiratory tract infections URTIs , supplementation is effective in reducing symptom severity.
Aerobic Exercise. There are no improvements in running performance in otherwise healthy athletes given this supplement for one month. Things to Note. Is a Form Of Immune Booster. Primary Function: Allergies and Immunity. Send me the course. Research Breakdown on Pelargonium sidoides. Link to This Close. Never miss an update! Your e-mail is safe with us. Very High See all 11 studies. Very High See all 12 studies. Very High See all 10 studies. High See all 9 studies.
Very High See all 4 studies. Very High See all 5 studies.
P elargonium sidoides, a plant native to coastal South Africa, is commonly known as South African geranium. Its mechanism of action may include a cytoprotective effect against viral attack, an antimicrobial effect through the release of defensins from neutrophilic granulocytes, and an immune-boosting effect through the release of tumor necrosis factor, nitrous oxide, and an increase in natural killer cell activity. Researchers have assessed the efficacy of P. One randomized double-blind study evaluated its safety and efficacy in patients with acute bronchitis treated by 36 primary care physicians. Success was based on change in bronchitis severity score over the 7-day treatment period.
Pelargonium sidoides Extract (EPs 7630)
This narrative review focuses on recently published results from RCTs investigating the clinical efficacy and safety of EPs in children and adolescents with different manifestations of aRTI, in order to present a broader overview and to provide an update on the state of knowledge regarding the use of EPs in this age-group. The Cochrane review on P. Reference lists of publications found were searched for relevant citations. Eight RCTs investigating the application of EPs in acute bronchitis, acute tonsil-lopharyngitis, and aRTI in the context of chronic preconditions were identified.